Technology > Therapeutic drSH3 targets
Next Biomed Therapies Oy is developing drSH3 domains targeted against a wide variety of therapeutically relevant proteins from different functional classes.
Fusion of these drSH3 molecules with themselves or existing therapeutic antibodies enables convenient construction in a plug-and-play fashion of powerful multi-specific proteins that can bind to several target proteins within and between these functional classes.
See here for examples of multi-specific drSH3-IgG fusion strategies
drSH3 = double-randomized SH3